Thus, leptin has been named "lipostat nature"

Leptin

(from the Greek letpo,

means "thin") is a 16-kDa, 146 - amino acid residue

protein produced mainly in adipocytes (fat cells). At high levels of leptin >> << injected daily in obese mice, animals decreased

food intake and increase the rate of oxidation of fats, losing 40% of its weight >> << month. Thus, leptin has been named "lipostat nature"

or "fat-stat", and thus this protein is of great interest in terms of

its potential to cause weight loss in humans. Half U.S. >> << population is overweight (at e

third obese [overweight by 20% or more

]), and the desire to lose weight national obsession. Usually

, as fat deposits accumulate lasix drug interactions in the fat cells more and more leptin is produced

in these cells and vyverhav into the bloodstream. The level of leptin in the blood

communicate the status of triglyceride levels in adipocytes in

central nervous system, so that appropriate changes in appetite occur. If leptin low ("starvation"), increased appetite, if the level of leptin

high ("overfeed"), appetite is suppressed. .